mismatch repair

Mismatch repair gene defects are recently identified in hematopoietic malignancies, leukemia and lymphoma cell lines.

错配修复基因缺陷是最近在造血系统恶性肿瘤, 白血病和淋巴瘤细胞株中被发现的.

Objective To explore the clinicopathologic features of sporadic colorectal cancers with mismatch repair deficiency and the application of the methods detecting the status of mismatch repair deficiency.

目的探讨错配修复缺陷的散发性大肠癌的临床病理特征及错配修复缺陷检测手段的应用。

Microsatellite instability was observed at one or more loci in a number of pancreatic cancers, but pancreatic cancers with mismatch repair deficiency may have an improved prognosis.

大多数胰腺癌在一个或多个位点有微卫星不稳定性，但有错配修复缺陷的胰腺癌可能预后良好。

MSI was significantly related with mismatch repair deficiency ( P < 0.01).

胃癌的MSI-H与错配修复蛋白表达的缺失高度相关（P<0.01）。

There are many DNA repair pathways to different DNA lesions, including base excision repair, nucleotide excision repair, mismatch repair and homologous recombination repair.

针对不同的DNA损伤。细胞内有许多不同的修复方式对其进行修复，包括碱基切除修复、核苷酸切除修复、错配修复、同源重组修复等。

The study of the mismatch repair deficiency of sporadic colorectal cancer

散发性大肠癌的错配修复缺陷研究